A photocross-linking fluorescent indicator of mitochondrial membrane potential.
نویسندگان
چکیده
منابع مشابه
Mitochondrial membrane potential: evidence from studies with a fluorescent probe.
The fluorescence of the probe 3,3'-dihexyl-2,2'-oxacarbocyanine (CC(6)) has been found to indicate potential across cell membranes. Results obtained in the present study using CC(6) and Drosophila mitochondria are in agreement with membrane potentials previously measured by Tupper and Tedeschi using microelectrodes. The results of both studies with Drosophila suggest that the potential across t...
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2-( Dimethylaminostyryl )-l-methyl pyridinium, a fluorescent indicator of mitochondrial membrane potential, is accumulated up to 400-fold by intact, isolated brown adipocytes from cold-adapted guinea pigs. The indicator can be optically localized within the in situ mitochondria. Ionophores which would be predicted to lower or increase the in situ mitochondrial membrane potential lead to decreas...
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Imaging activity of neurons in intact brain tissue was conceived several decades ago and, after many years of development, voltage-sensitive dyes now offer the highest spatial and temporal resolution for imaging neuronal functions in the living brain. Further progress in this field is expected from the emergent development of genetically encoded fluorescent sensors of membrane potential. These ...
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Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...
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OBJECTIVE Maintenance of the mitochondrial membrane potential (Deltapsim) is fundamental for the normal performance and survival of cells such as cardiomyocytes, that have a high energy requirement. Measurement of Deltapsim is therefore essential in order to develop an understanding of the molecular mechanisms controlling cardiomyocyte function. Here we have evaluated various potentiometric dye...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1993
ISSN: 0022-1554,1551-5044
DOI: 10.1177/41.4.8450203